Life Extension NAD+ Cell Regenerator Nicotinamide Riboside, 30 Capsules(2 Pack)

Love this stuff. It has always been one of the more expensive supplements but gives me a lasting energy throughout the day. I take 2-3 capsules first thing upon waking with a glass of water. It is one of the few supplements that I actually have a noticeable result when taking.

This is some interesting stuff. I'm not looking to extend my life with it, but I am interested in being as healthy as I can be until I die. Had a heart valve replaced in Oct 2017, so i thought I'd try this supplement as part of my rebuilding process. About 2 weeks in I notice that my elbows, knees and the bottoms of my feet were much softer and less brittle than previously. if that same effect is going on all over my body, I'm quite pleased with the results. The skin is a major organ, so I am grateful for the improvement given my age.I'm only taking one a day at bedtime so far, but I am considering upping my dosage to 2x/day. I'm 65 and not rich so money is a consideration here. As far as I'm concerned, a good supplement value for the price.

I've been taking a combination of pterostilbene and this nicotinamide riboside for inside of five months ... I think less even, perhaps ... and I have not FELT any different, but there have been some jaw dropping results. I don't know which supplement is responsible, but have I ever got a tale to tell. The less amazing result was a pretty drastic drop in the LDLs of my last blood lipid profile from around 100 to 66, and a modest increase in my HDLs from around 35 to 40. I've done nothing else that could reasonably result in such a change, and I have been taking a statin (atorvastatin) and megadoses (about 1500 mg)of buffered niacin for many years with some good results, but nothing like this. But the REALLY amazing thing is what happened after I laid down about 2700 lbs of topsoil, sand and manure on my backyard garden manually from waist high level. 57 bags weighing between 45 and 50 lbs I laid down, half expecting to either hurt my back (I've had back problems for many years) or else end up basically unable to get out of bed the next morning. Now, I'm 63 years old, and I haven't worked that hard, I think, in almost 30 years. I expected to suffer from all that work, and of course when I finished I was dead tired and even wobbly on my feet. I awoke feeling only slight stiffness, no soreness at all. The next day, when I expected to be more stiff and quite sore instead the stiffness was gone and still no soreness. Mind you, I don't work out much and I'm really not in great shape, so this to me seems well nigh impossible.For reference, I've been taking 100mg of the pterostilbene and 375mg of the nicotinamide riboside daily for a while, having started out with only 200 to 300mg of the latter daily. I have just now increased my pterostilbene intake by double and increased my nicotinamide riboside to 500 mg. That's about all I can afford on my budget, but I consider it money well spent if it will do this for me.

If you want to know more about this supplement, look at the videos posted by David Sinclair. Dr. Sinclair is a professor at Harvard and also at the same time at the University of New South Wales. He is one of the leading researchers in the field of life extension.It has been known since the 1930s that life and health could be extended by restricting calorie intake. This experiment has been repeated over and over on many different species. It invariably works. The problem for humans has been that very few people are willing to restrict their calorie intake by the 30% required.David Sinclair and his group have been working to find the biological basis for the life extending effect of calorie restriction. They were the ones who were involved in the discovery of resveratrol. This supplement is the next step in supplements to mimic calorie restriction. At this point it looks as though the effect is accomplished by activating Sirtuin genes, mainly SIRT1.The full story has not been worked out. It probably won't be for a long time. But we know at this point that taking this particular supplement will extend lifespan and health. If you are lucky, it will extend your life long enough to take advantage of better therapies as they come along. But there is, of course, no guarantee.I am 75 years old. I am not in good health. Honestly I have been feeling as though I was dragging my way along to the end-of-life always tired, with too little energy to do much more than read and watch TV. A nap every afternoon started about 4 years ago when a disc collapsed making it too painful to continue working.The same day I took the first of these capsules, I could feel an energy increase. I tried to nap as usual. But I just wasn't tired. I didn't fall asleep. And today for the first time in a long time I walked 1.6 miles over 45 minutes with my son who was playing Pokeman Go. I just feel better.

I take others nootropics in combination with these NAD+ pills, the days i took my other pills without these i felt my mood wasmore "grumpy" and the days i took these i felt more relaxed and with a clearer thoughts, will keep making placebo tests to seeif it really makes a difference in my mood.

This is a great supplement for older adults. I am taking it to assist in my cancer treatment. Love it.